Innate Immunity in the Pathogenesis of Cholangiopathy: A Recent Update
نویسندگان
چکیده
منابع مشابه
Innate immunity in the pathogenesis of cholangiopathy: a recent update.
Biliary innate immunity is involved in the pathogenesis of cholangiopathies in patients with various biliary diseases. Biliary epithelial cells possess an innate immune system consisting of the Toll-like receptor (TLR) family and recognize pathogen-associated molecular patterns (PAMPs). Recently, regulatory mechanisms by intracellular negative regulators including peroxisome proliferator-activa...
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Biliary innate immunity is involved in the pathogenesis of cholangiopathies in cases of biliary disease. Cholangiocytes possess Toll-like receptors (TLRs) which recognize pathogen-associated molecular patterns (PAMPs) and play a pivotal role in the innate immune response. Tolerance to bacterial PAMPs such as lipopolysaccharides is also important to maintain homeostasis in the biliary tree, but ...
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ژورنال
عنوان ژورنال: Inflammation & Allergy-Drug Targets
سال: 2012
ISSN: 1871-5281
DOI: 10.2174/187152812803589976